To commemorate the World Sight Day taking place on the 14^th of October, DARTER is organizing a one-day webinar on eye research. We have gathered a panel of experts in the field giving our audience the opportunity to learn from and network with these leading scientists in ophthalmic, genetic and therapeutics research.

 

The webinar is divided into three main blocks:

Block 1: Retinal processing, models, and biomarkers of diseases.

Block 2: Retinal phenotypes and Therapeutics Part I

Block 3: Retinal phenotypes and Therapeutics Part II

 

The webinar is free and will take place on October 14th, 2021 from 10 a.m. to 6:30 p.m. (GMT+2, Brussels time) via Zoom. If interested, please don’t forget to register below!

We hope to see you there,

The organizer committee,

Mirella Barboni (Semmelweis University, Budapest, Hungary)

Alex Garanto (Radboudumc, Nijmegen, The Netherlands)

Aurélie Goyenvalle (Université Paris-Saclay, Versailles, France)

Irene Vázquez Domínguez (Radboudumc, Nijmegen, The Netherlands)

Tomasz Tomkiewicz (Radboudumc, Nijmegen, The Netherlands)

 

Preliminary Program

DARTER RETINA 2021

14^th of October – Virtual (Zoom)

10.15 – 10.20 Welcome and introduction (Mirella Barboni)

All presentations are 20-minute long with 5-minute interval for Q&A

First block: Retinal processing, models, and biomarkers of diseases (10.20-12.25)

Moderators: Irene Vázquez Domínguez and Tomasz Tomkiewicz

• 10:20 – 10.40: How does the retina work? Christina Joselevitch, Medical Manager Eye Care, Allergan GmbH, Germany
• 10:45 – 11.05: (pro’s and con’s of) In vivo and in vitro models. Dunja Lukovic, Research Center Principe Felipe, Spain 
• 11:10 – 11.30: Molecular readouts and retinal organoid technology to investigate retinal disease. Julio Corral-Serrano, UCL Institute of Ophthalmology, UK
• 11:35 – 11:55: Electrophysiological readouts of retinal integrity in mice. Jan Kremers, University Hospital Erlangen, Germany
• 12:00 – 12.20: Ophthalmological readouts (OCT, fundus, adaptative optics). Peter Maloca, Institute of Molecular and Clinical Ophthalmology, Switzerland

 

Lunch break and spatial chat (12.25-13.25)

Second block: Retinal phenotypes and therapeutics – part I (13.25-15.30)

Moderator: Aurélie Goyenvalle

• 13:25 – 13.45: Complexity of IRDs, clinical and genetic heterogeneity. Susanne Roosing, Radboud University Medical Center, the Netherlands
• 13:50 – 14.10: Brief overview on molecular therapeutic approaches and delivery for IRDs. Alex Garanto, Radboud University Medical Center, the Netherlands
• 14:15 – 14.35: Human and mouse visual phenotypes in DMD. Mirella Barboni, Semmelweis University, Hungary
• 14:40 – 15.00: Rescue of Dp71 expression in the retina and restoration of retina function in Dp71-null mice after AAV treatment. Cyrille Vaillend, University Paris-Saclay, France
• 15:05 – 15.25: Visual restoration in mice with CSNB.Christina Zeitz, Institut de la Vision, France

 

Coffee break and spatial chat (15.30-16.00)

Third block: Retinal phenotypes and therapeutics – Part II (16.00 -18.10)

Moderator: Alex Garanto

• 16:00 – 16.20: CNGA and CNGB gene therapy trials. Ditta Zobor, University of Tübingen, Germany and Semmelweis University, Budapest, Hungary
• 16:25 – 16.45: Exon skipping therapy for USH2A. Erwin van Wijk,Radboud University Medical Center, the Netherlands
• 16:50 – 17.15: NR2E3 degradation using AONs. Elfride De Baere,Ghent University, Belgium
• 17:20 – 17.40: Therapeutic Strategies for Intronic ABCA4 Variants in Stargardt Disease. Rob Collin, Radboud University Medical Center, the Netherlands
• 17:45 – 18.10: Delivery of gold nanoparticles to retinal cells. Sonia Trigueros & Gemma Marfany, University of Barcelona, Spain  

18.10 – 18.20 Closing and farewell (Mirella Barboni)

Registration: