Italy

 

COST Action Members form Italy

 

ClaudioNastruzi

Prof. Claudio Nastruzzi

RESEARCH TOPIC

The main goal of the Laboratory is an integrative concept of research and teaching in the fields of biomaterials, bioencapsulation, drug formulation and drug delivery. Currently are under investigation different formulations including, inorganic matrixes, liposomes, lipospheres, microparticles, nanocapsules, microemulsions and polymeric films. For the development of such delivery systems, we are in close cooperation with other groups in the basic, engineering, medical sciences and pharmaceutical industry. Another important field of study is represented by cell encapsulation and transplantation using natural, synthetic and engineered polymers. The research group focuses on the development of biomaterials and delivery systems for drugs, biological response modifiers, biotech products and cosmetics. Production and characterization of particulate delivery systems are investigated, including liposomes and microspheres for gene therapy. In particular, new formulations, have been designed and produced for Natural and Peptide (PNA) Nucleic Acids, based on cationic polymeric sub-micron particles constituted by Eudragit RS 100 plus different cationic surfactants.
Moreover, the design and production of advanced cosmetic formulations have been accomplished, based on liquid crystals, microparticles in association with hydrophilic polymers and polymeric surfactants. The laboratory also has expertise in tissue engineering and cell encapsulation protocols (pancreatic islets, Sertoli cells, osteoblasts, etc.) and biocompatibility tests for the validation of biomaterials. The rapid prototyping section focuses on the design and development of small laboratory equipment for biotech applications and microencapsulation protocols. Finally, the laboratory know-how has expanded to the design, production and use of microfluidic chip for the production of nanoparticles and microparticles.

Affiliation

Dept. of Chemical and Pharmaceutical Sciences,
Claudio Nastruzzi,
University of Ferrara

via Luigi Borsari 46, 44121 Ferrara
Ferrara, Italy

ORCID: 0000-0001-9552-0807

WWW: www.biomaterials.it

 

ACTION MEMBER

MEMBER OF WG1, INTERESTED IN WG2 TASKS

KEYWORDS: delivery strategies, nanoparticles, colloidal systems

MODEL: cell culture

TISSUE: bone and cartilage

DISORDERS: Ocular diseases, Diabetes, Skin diseases

 

woman ikoneDr Elisa GIORGIO
Affiliation: Medical Genetics Unit, Dep. Medical Sciences, University of Torino, Italy
ORCID: 0000-0003-4076-4649
Webpage:

COST function: MC Member
COST Working Groups:

 

 

Research interests:
keywords: Autosomal Dominant Leukodystrophy, allele-specific silencing, siRNAs, gene duplications, neurodegenerative disorders, position effect mutations, regulatory mutations, topologically associating domains (TADs)
disorders:
tissue/organ of interest:
model system(s):

woman ikoneProf Michela Alessandra DENTI 
Affiliation: CIBIO, University of Trento, Trento, Italy
ORCID: 0000-0001-7203-7062
Webpage: https://www.cibio.unitn.it/98/laboratory-of-rna-biology-and-biotechnology

COST function: MC Member, WG4 Leader, Training School Coordinator
COST Working Groups: WG 1 - Delivery Strategies, WG 2 - Model systems, WG 3 - Safety and toxicology, WG 4 - Stakeholder communication and dissemination

Research interests:
keywords: RNA Biology, therapeutical exon skipping, antisense oligonucleotides, U1 snRNA, frontotemporal dementia, neurodegenerative diseases, microRNAs, cancer, biomarkers, rare diseases
disorders: Lysosomal Storage Disorders, Inherited retinal disease, neurodegenerative disorders, dementias
tissue/organ of interest: Brain, Eye
model system(s): Cell culture, Mouse

woman ikoneDr Elena BATTAGLIOLI
Affiliation: University of Milan, Milan, Italy
ORCID: 0000-0001-9168-7212
Webpage:

COST function: Member
COST Working Groups: WG 2 - Model systems

 

 

Research interests:
keywords: epigenetics, transcription, Rett syndrome
disorders: Rett syndrome
disorders: Neuromuscular disorders, Duchenne muscular dystrophy
tissue/organ of interest: Brain
model system(s): Mouse

 

man ikoneProf Alfredo BRUSCO
Affiliation: University of Torino, c.so Dogliotti, 14, Italy, Torino
Research Group:
ORCID:
Webpage:

COST function: Substitute MC Member
COST Working Groups:

 

Research interests:
keywords:
disorders:
tissue/organ of interest:
model system(s):

woman ikoneDr Elisa GIORGIO
Affiliation: University of Torino, Torino, Italy
ORCID:
Webpage:

COST function: Member
COST Working Groups: WG 1 - Delivery Strategies

 

 

Research interests:
keywords: ASP-silencing, CNS delivery
disorders: Leukoencephalopaties and ataxias
tissue/organ of interest: Brain
model system(s): Cell culture, Mouse, Human

woman ikoneDr Giusy COVELLO
Affiliation: CIBIO, University of Trento, Trento, Italy
Research Group: Michela A Denti Group
ORCID: 0000-0001-5660-8283
Webpage: https://www.researchgate.net/profile/Giuseppina_Covello

COST function: Member
COST Working Groups: WG 1 - Delivery Strategies, WG 2 - Model systems, WG 3 - Safety and toxicology

 

Research interests:
keywords: AONs, siRNA, Delivery, Brain, Eye, Gene Therapy strategies
disorders: Metabolic diseases, Inherited retinal disease, Neurodegenerative Disease
tissue/organ of interest: Brain, Eye
model system(s): Cell culture, Mouse

man ikoneFrancesco RUSCONI
Affiliation: University of Milan, Milan, Italy
ORCID: 0000-0003-0500-7845
Webpage:

COST function: Member
COST Working Groups: WG 1 - Delivery Strategies

 

 

Research interests:
keywords: epigenetics depression anxiety neuropsychiatric disorders
disorders: neuropsychiatric disorders
tissue/organ of interest: Brain
model system(s): Cell culture, Mouse

Learn more about Researchers from DARTER's Member Countries

Belgium Bosnia and Herzegovina Croatia Cyprus Czech Republic Denmark Estonia France Germany greece Hungary Ireland Israel Italy
Latvia Malta Netherlands Norway Poland Portugal Romania Serbia Slovenia Spain Sweden Turkey United kingdom  

 

Page top

0
0
0
s2smodern