Purpose of the STSM: The main goals of my PhD project are to: 1. Understand the role of alternative splicing in pancreatic β-cell dysfunction and death in the context of type 1 diabetes (T1D); 2. Identify key splicing factors and harmful mRNA splice variants that can be modulated using antisense oligonucleotides (ASOs) to prevent β-cell loss…
Grantee name: Maria Inês Alveolos (ULB Center for Diabetes Research. Medical Faculty, Universite Libre de Bruxelles, Belgium)
STSM start and end date: 2019-02-03 to 2019-02-24
Title: SRp55 splicing landscape and AONs-based splicing modulation
Host lab: Kathi Zarnack’s Laboratory. Buchmann Institute for Molecular Life Sciences. Frankfurt, Germany.