Purpose of the STSM:
…Previous observation suggested that oligonucleotides could interfere with the transcriptional process of the target thereby reducing the efficiency of the therapeutic approach. the purpose of this STSM was to assess the side-effect of antisense therapy on the transcriptional output of the target locus.
Grantee name: Raquel García Rodríguez (Centro de Biología Molecular Severo Ochoa, Madrid, Spain.)
STSM start and end date: 2019-02-01 to 2019-04-30
Title: Assesment of side effects of antisense therapy on the transcriptional output in Duchenne Muscular Dystrophy (DMD)
Host lab: Pietro Spitali’s Laboratory. Human Genetics Department. Leiden University Medical Center. Leiden, Netherlands.